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a bottle and glass of Caymus wine on a wooden table
Two bottles of alcohol with sale prices and Deep Discounts in a festive autumn setting.
a bottle of Peerless Bourbon on a barrel
bottle of Weis Vineyards rosé on a wooden table
bottle of Tincup whiskey outdoors with fire in background

Welcome to
Lisa’s Liquor Barn Local & National Favorites

We are proud to be one the premier provider of wines and spirits in Rochester NY. For over 35 years we’ve been striving to offer the region’s most diverse collection of spirts, wine, cordials and all your other favorites. As one of the most popular and established Penfield liquor stores, you can have confidence in our vast selection, fair prices and the kind of personable service honed over three decades. We invite you to stop in or order online today!

Wine & Spirits for Every Occasion
The best selection of wine and spirits in Upstate New York

Shop Wines

Staff Picks

When we say that our staff knows its wine and spirits, you can take us at our word. And we’re constantly looking for ways to help you enjoy the best there is at unmatched prices. Here are just a few of our current staff picks, get in touch to discover others!

View All Staff Picks

Stop in today to learn more, or give us a call at 585-377-1860. Thanks for making Lisa’s Liquor Barn the best place to shop for wine and spirits in Rochester!